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KMID : 0613320110170010017
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Journal of the Korean Bone and Joint Tumor Soceity
2011 Volume.17 No. 1 p.17 ~ p.22
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Chondrosarcoma Arising from Benign Bone Tumor due to Malignant Transformation
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Cho Wan-Hyeong
Song Won-Seok
Kong Chang-Bae
Hong Youn-Seok
Lee Jeong-Dong
Jeon Dae-Geun
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Abstract
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Purpose:We analyzed the oncological outcome and prognostic factor of the chondrosarcoma arising from benign bone tumor due to malignant transformation.
Materials and Methods :From April 1986 to April 2009, 18 cases were considered eligible. We analyzed retrospectively the patient’s characteristics and prognostic factors that affect to the local recurrence and distant metastasis.
Results:As classified by primary benign bone tumor, 4 cases were solitary osteochondroma, 11 cases were multiple osteochondromatosis and 3 cases were multiple enchondromatosis. The mean follow-up period was 85 months. The 5-year disease free survival rate of 18 patients was 85.9%. Their overall MSTS score was 25.2 (84%). There were local recurrence in 3 cases and no distant metastasis. We found that tumor location and surgical margin affected to the prognosis significantly.
Conclusion:In secondary chondrosarcoma patients, the prognosis was good relatively and tumor location and surgical margin are important prognosis factor.
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KEYWORD
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chondrosarcoma, maliganant transformation, prognostic factor
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